Industry News
Risk For Testicular Cancer Increases With Genetic Copy-Number Variants
Aug 05, 2012
Genetics clearly plays a role in cancer development and progression, but the reason that a certain mutation leads to one cancer and not another is less clear. Furthermore, no links have been found between any cancer and a type of genetic change called "copy-number variants," or CNVs... Read More
Breast Cancer Slowed By Plant-Based Compound In Mouse Model
Aug 05, 2012
The natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumors in a mouse model with similarities to human breast cancer progression, according to a study published in the Journal of the National Cancer Institute. Edible plants are gaining ground as chemopreventative agents... Read More
Breast Cancer Slowed By Plant-Based Compound In Mouse Model
Aug 05, 2012
The natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumors in a mouse model with similarities to human breast cancer progression, according to a study published in the Journal of the National Cancer Institute. Edible plants are gaining ground as chemopreventative agents... Read More
How Protein Component That Enables Cell Replication Gets Ferried To Chromosome Tips
Aug 04, 2012
Stem cells are special. Nestled in muscle and skin, organ and bone, they bide their time over years or decades until called to replace damaged or lost tissue. One secret to their longevity is an enzyme called telomerase, which stills the relentless ticking of the molecular clock that limits the life span of other cells... Read More
Afinitor Approved In Europe For Advanced Breast Cancer
Aug 04, 2012
E.U. approval has been granted to Novartis drug Afinitor® (everolimus) after successful completion of the Phase III BOLERO-2 (Breast cancer trials of OraL EveROlimus-2) trial... Read More
Afinitor Approved In Europe For Advanced Breast Cancer
Aug 04, 2012
E.U. approval has been granted to Novartis drug Afinitor® (everolimus) after successful completion of the Phase III BOLERO-2 (Breast cancer trials of OraL EveROlimus-2) trial... Read More
Mechanism Of Lung Cancer-Associated Mutations Suggests New Therapeutic Approaches
Aug 03, 2012
Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors... Read More
News From The Journal Of Clinical Investigation: Aug. 1, 2012
Aug 03, 2012
ONCOLOGY Chemokine pathway suppresses colon cancer metastasis Chemokines are signals in the body that act as beacons, calling out to migrating cells, such as white blood cells, guiding them to where they are needed... Read More
First Genome-Wide Analysis Of Peripheral T-cell Lymphomas Identifies 13 Novel Alterations In This Aggressive Blood Cancer
Aug 03, 2012
Researchers at Mayo Clinic have completed the world's first genome-wide sequencing analysis of peripheral T-cell lymphomas, unlocking the genetic secrets of this poorly understood and highly aggressive cancer of the immune system. Andrew Feldman, M.D... Read More
3 Related Studies Help Uncover The Rules Governing Gene Transcription
Aug 03, 2012
A trio of groundbreaking publications from researchers in Northwestern University's Physical Sciences-Oncology Center (PS-OC) report important methodological advances that will enable a better understanding of how gene expression is regulated, both in normal cells and in cancer cells. This knowledge could lead to the development of more effective therapeutic agents to treat cancer patients... Read More
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