Industry News
Novel T-Cell Therapy Eradicates An Aggressive Leukemia In 2 Children
Mar 26, 2013
Two children with an aggressive form of childhood leukemia had a complete remission of their disease - showing no evidence of cancer cells in their bodies - after treatment with a novel cell therapy that reprogrammed their immune cells to rapidly multiply and destroy leukemia cells... Read More
New DNA Test To Detect Mutations Across 46 Genes In NHS Patients With Solid Tumour (UK)
Mar 26, 2013
The first multi-gene DNA sequencing test that can help predict cancer patients' responses to treatment has been launched in the National Health Service (NHS), thanks to a partnership between scientists at the University of Oxford and Oxford University Hospitals NHS Trust... Read More
Negative NICE Decision For AvastinĀ® (Bevacizumab) Highlights Challenges Facing UK Access To Medicines
Mar 26, 2013
Roche is disappointed that the National Institute for Health and Clinical Excellence (NICE) has published a negative final recommendation (FAD) for the use of Avastin (bevacizumab) in combination with paclitaxel and carboplatin for women with newly-diagnosed advanced ovarian cancer*... Read More
News From The Journal Of Clinical Investigation: March 25, 2013
Mar 26, 2013
A new therapeutic target in iron overload disorders Iron is required for multiple cellular functions, including the synthesis of hemoglobin, but a buildup of excess cellular iron can be toxic. Hepcidin is a circulating molecule produced by the liver that triggers the degradation of iron transporters in the intestine and certain immune cells... Read More
Experts Examine Profiles From Patients With Early Stage Lung Adenocarcinoma, Identify Patterns Of Mutations To Help Inform Design Of Future Trials
Mar 26, 2013
Molecular driven therapeutic targets have resulted in a paradigm shift in the treatment of advanced lung adenocarcinoma. However, in early non-small cell lung cancer (NSCLC), surgical resection remains the treatment of choice with adjuvant chemotherapy... Read More
For Rapidly Increasing Form Of Esophageal Cancer, Molecular 'Signature' Found
Mar 26, 2013
During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States... Read More
How Cells Interact With Surroundings: Computer Simulations Have Implications For Cancer, Atherosclerosis Research
Mar 26, 2013
Your cells are social butterflies. They constantly interact with their surroundings, taking in cues on when to divide and where to anchor themselves, among other critical tasks. This networking is driven in part by proteins called integrin, which reside in a cell's outer plasma membrane... Read More
Research On Immune-Cell Therapy Could Strengthen Promising Melanoma Treatment
Mar 26, 2013
A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer... Read More
The Considerable Gender Differences In Cardiovascular Disease, Cancer, Liver Diseases, Osteoporosis, And Pharmacology
Mar 26, 2013
At the dawn of the third millennium medical researchers still know very little about gender-specific differences in illness, particularly when it comes to disease symptoms, influencing social and psychological factors, and the ramifications of these differences for treatment and prevention. Medical research conducted over the past 40 years has focused almost exclusively on male patients... Read More
Young Adult Cancer Deaths Cut In Half In The U.K.
Mar 25, 2013
The number of deaths among teenagers and young adults due to cancer in the UK has been cut in half since the 1970s, according to new data from Cancer Research UK. The number of deaths among children and young adults dropped from close to 580 annually in 1975-1977 to 300 in 2008-2010. The largest reduction was in young patients with leukemia... Read More
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