Industry News
Sensitizing Human Ovarian Cancer Cells To A Targeted Cytotoxic Drug
May 31, 2013
A novel, targeted approach to chemotherapy that makes ovarian cancer cells more susceptible to the cytotoxic effects of an antitumor drug may offer a safer, more effective treatment option for this often deadly form of cancer. The research and results are published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers... Read More
Stem Cell Matrix -- A Summary Of Recent Studies From Harvard Stem Cell Institute
May 31, 2013
May brought a major advancement in the science of aging when two Harvard Stem Cell Institute (HSCI) researchers announced their discovery of a protein circulating in the blood of mice and humans that shows potential to be a treatment for age-related heart failure. The protein, called GDF-11, reduced the size and thickness of the heart walls when injected into old mice... Read More
Longer Treatment For Children With Langerhans Cell Hystiocytosis Improves Survival Rates
May 31, 2013
A new international study finds that prolonged, intense initial treatment in children with multi-system Langerhans cell histiocytosis (MS-LCH) can achieve survival rates as high as 84 percent - a full 15 percent improvement over the previous clinical trial in this series. The study, LCH-III, is published in Blood, the journal of the American Society of Hematology... Read More
For Patients With Stage III Lung Cancer, Higher-Dose RT Results In Inferior Survival
May 31, 2013
In a randomized phase III clinical trial conducted by the Radiation Therapy Oncology Group (RTOG), high-dose (HD), compared with standard-dose (SD), radiotherapy (RT) with concurrent chemotherapy (CT) did not improve overall survival of patients with stage III non-small-cell lung cancer (NSCLC)... Read More
Best Treatment For High-Risk Low-Grade Glioma Is Still Radiotherapy
May 31, 2013
In a large, international, randomized trial, initial radiotherapy was compared to temozolomide chemotherapy. A statistically significant difference between the two treatment strategies was not observed for progression-free survival, although radiotherapy was numerically favored... Read More
Patients With Anaplastic Oligodendroglioma Identified Who May Benefit From Adjuvant PCV
May 31, 2013
A further report on the results of EORTC trial 26951 indicates that CpG island methylator phenotype (CIMP) status and O 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation as assessed by MGMT-STP27 are the most informative for identifying grade III glioma patients who might benefit from the addition of procarbazine, CCNU and vincristine (PCV) chemotherapy to radiation therapy... Read More
Complication Risk After Breast Reconstruction Affected By Weight Of Tissue Flaps
May 31, 2013
For women undergoing breast reconstruction after mastectomy, the weight of the tissue flap used affects the risk of an important complication called fat necrosis, reports a study in Plastic and Reconstruction Surgery-Global Open®, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS)... Read More
Previously Unidentified Cells Offer Potential Targets For Future Treatments Of Prostate Cancer
May 31, 2013
Researchers have identified a sub-group of cells that could contribute to prostate cancer recurrence, opening up new ways to treat the disease, which claims more than 3000 lives a year in Australia. Published in Science Translational Medicine, a study led by Monash University researchers has found prostate cancer cells that survive androgen withdrawal treatment... Read More
Study Finds That Radiation Oncology Research Is Critically Underfunded By The National Institutes Of Health (NIH)
May 31, 2013
Radiation oncology research received 197 grants, totaling only 1.6 percent ($85.5 million) of the $5... Read More
Identification Of A Novel Way In Which 'Junk DNA' Can Interfere With The Normal Functioning Of A Cell, Leading To Cancer Progression
May 31, 2013
Scientists at The University of Nottingham have found that a genetic rogue element produced by sequences until recently considered 'junk DNA' could promote cancer progression... Read More
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