Industry News
Master Regulator Discovered In Cancer Metastasis
Jun 12, 2013
The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance... Read More
Novel Targeted Therapies With Fewer Harmful Side Effects
Jun 12, 2013
Conventional treatments for diseases such as cancer can carry harmful side effects - and the primary reason is that such treatments are not targeted specifically to the cells of the body where they're needed... Read More
HDAC3 In Stem Cell Functions Essential For Blood Cell Development
Jun 12, 2013
The expression of specific genes is partially dictated by the way the DNA is packed into chromatin, a tightly packed combination of DNA and proteins known as histones. HDAC3 is a chromatin-modifying enzyme that regulates gene expression, chromatin structure, and genome instability and it has previously been shown to associate with the oncoproteins that drive leukemia and lymphoma... Read More
Breast Cancer Screening Does Not Reduce Deaths Says Study Of 40 Years Of Mammograms
Jun 11, 2013
A new UK study suggests screening for breast cancer does not reduce deaths from the disease. The study, which looked at nearly 40 years of breast screening, adds to the controversy surrounding whether it is screening or improvement in treatment that accounts for the fall in rates of death from breast cancer... Read More
Glycotope Reported Promising First-in-Man Data At ASCO 2013 For Its Glycooptimized Anti-EGFR Antibody CetuGEXTM To Treat Solid Tumors
Jun 11, 2013
Glycotope GmbH, a global leader in optimizing the sugar chains (glycosylation) of biopharmaceuticals, announced full details of first-in-man Phase I trial data for CetuGEXTM, an anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) with optimized and fully human glycosylation for a greatly enhanced anti-tumor activity and reduced side-effects... Read More
Gastrointestinal Endoscopes At 5 US Hospitals Analyzed For Presence Of 'Bio Dirt' - 3 Out Of 20 Improperly Cleaned
Jun 11, 2013
Three out of 20 flexible gastrointestinal (GI) endoscopes used for screening were found to harbor unacceptable levels of "bio dirt" - cells and matter from a patient's body that could pose potential infection risk - according to a study of endoscopes used at five hospitals across the U.S... Read More
VU Study Identifies New Mechanism For Cancer Development
Jun 11, 2013
Researchers at Vanderbilt University Medical Center led by a 32-year-old postdoctoral fellow have discovered a new mechanism for the development of cancer that is challenging conventional scientific wisdom. Bhuminder Singh, Ph.D... Read More
New Targets In Diverse Cancers Identified Via Clinical Sequencing Technology
Jun 11, 2013
Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research... Read More
FDA Approves Scalp-Cooling For Chemo Hair Loss Final Trial
Jun 11, 2013
Dignitana, a world leader in medical scalp-cooling technology, has announced that it has received U.S. Food and Drug Administration (FDA) approval for its Investigational Device Exemption (IDE) application and is now free to initiate a highly anticipated multi-center, pivotal trial of the patented DigniCap® System... Read More
Potential Drug Target Identified For Treatment-Resistant Anemias
Jun 11, 2013
Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy... Read More
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