Industry News
Absence of specific enzyme in cartilage can lead to benign tumors in mice
Jul 23, 2013
Rhode Island Hospital researchers have found that the absence of the Shp-2 enzyme near specialized cartilage cells can lead to the development of multiple benign cartilage tumors in mice, a model that recapitulates the rare human tumor syndrome metachondromatosis. Shp2 is an enzyme in the cell that regulates the activity of other proteins and signaling pathways... Read More
In EORTC trial for patients with desmoid-type fibromatosis, moderate dose radiotherapy effective
Jul 23, 2013
A phase 2 EORTC trial for patients with inoperable desmoid-type fibromatosis has shown that moderate dose radiotherapy is an effective treatment for patients with such a rare type of tumor. The study results published in Annals of Oncology show that response after radiation therapy is slow, and that continuing regression is seen even after three years. Dr. Ronald B... Read More
Time between cancer diagnosis and treatment provides 'window of opportunity' to optimize health
Jul 23, 2013
For patients with cancer, "prehabilitation" - interventions given between the time of diagnosis and the start of treatment - has the potential to reduce complications from treatments and improve physical and mental health outcomes, according to a report in the August American Journal of Physical Medicine & Rehabilitation (AJPM&R)... Read More
HPV linked to a third of throat cancers
Jul 22, 2013
One third of people with cancers in the back of the throat (oropharyngeal cancers) are infected with a certain strain of human papillomavirus (HPV), according to new research published in the Journal of Clinical Oncology at the weekend... Read More
Half a million UK cancer survivors faced with disability and poor health, UK
Jul 22, 2013
At least one in four people living with cancer - over 500,000 in the UK[1] - experience a wide range of long-term debilitating health conditions caused by their cancer, according to a new report by Macmillan Cancer Support... Read More
Proteomics can improve breast cancer treatment
Jul 22, 2013
Researchers at Karolinska Institutet in Sweden have identified a protein that could help physicians decide what type of therapy patients with hormone driven breast cancer should go through... Read More
The malignant march of cancer cells slowed by thwarting protein production
Jul 22, 2013
Protein production or translation is tightly coupled to a highly conserved stress response that cancer cells rely on for survival and proliferation, according to Whitehead Institute researchers... Read More
Innovative technique can tell if drugs have hit their target in the human body
Jul 22, 2013
The search for new drugs, including those for cancer, is set to speed up thanks to a new research technique invented by scientists at the Nanyang Technological University (NTU). Named the "Cellular Thermal Shift Assay" (CETSA), scientists can now know for sure if a drug had reached its target protein in the body, which is a critical step in determining the effectiveness of most medicines... Read More
Compounds outsmart solid tumors' malfunctioning machinery
Jul 22, 2013
Molecular biologists in the School of Medicine at The University of Texas Health Science Center San Antonio have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting effects. This machinery, the proteasome, is deregulated in cancer... Read More
Breast cancer patients benefit from treatments tailored specifically for their tumor types
Jul 22, 2013
The Side-Out Foundation's breast cancer pilot study, led by the Translational Genomics Research Institute (TGen), Translational Drug Development (TD2) and Scottsdale Healthcare, has shown that cancer patients do better when their treatment is guided by molecular profiling... Read More
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