Industry News
One important way in which EGFR may derail the body's cancer-fighting autophagy machinery to increase tumor growth
Sep 20, 2013
Overactivity of a protein that normally cues cells to divide sabotages the body's natural cellular recycling process, leading to heightened cancer growth and chemotherapy resistance, UT Southwestern Medical Center researchers have found. The epidermal growth factor receptor, or EGFR, is found at abnormally high levels on the surface of many types of cancer cells. The study, led by Dr... Read More
Breast conserving treatment with radiotherapy reduces risk of local recurrence
Sep 20, 2013
Results of EORTC trial 10853 appearing in the Journal of Clinical Oncology show that breast conserving treatment combined with radiotherapy reduces the risk of local recurrence in women with ductal carcinoma in situ (DCIS). The incidence of DCIS has been increasing in the past decades, and this has been attributed to increased detection through breast cancer screening using mammograms... Read More
Trade-offs for fair skin
Sep 20, 2013
The proclivity of Spaniards to bask in regions like the Costa del Sol while their northern European counterparts must stay under cover to protect their paler skin or risk skin cancer is due in large part to the pigment producing qualities of the MC1R gene locus. The MC1R gene, expressed in skin and hair follicle cells, is more diverse in Eurasian populations compared to African populations... Read More
Life or death for cells could hinge on a protein
Sep 20, 2013
Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum (ER), which is able to sense cellular stress and trigger either rescue responses or the death of the cell... Read More
New technology presented at OSA's Frontiers in Optics meeting will help fight cancer
Sep 20, 2013
Scientists seeking new ways to fight cancer often try to understand the subtle, often invisible, changes to DNA, proteins, cells, and tissue that alter the body's normal biology and cause disease. Now, to aid in that fight, a team of researchers has developed a sophisticated new optical imaging tool that enables scientists to look deep within tumors and uncover their inner workings... Read More
Diversity of microbial growth strategies in a limited nutrient world
Sep 20, 2013
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast... Read More
New technique speeds up cancer diagnosis during surgery
Sep 20, 2013
Tissue-conserving cancer surgery is a highly skilled procedure which involves time-consuming tissue preparation to detect the margins of cancerous tissue. The goal is to remove as much of the tumour as possible while sparing healthy tissue... Read More
Shorter radiotherapy for early breast cancer 'best option'
Sep 20, 2013
Results from a 10-year study confirm that giving radiotherapy to women with early breast cancer in a lower overall dose through fewer, higher doses is at least as effective and safe as the current standard of a higher overall dose. The finding comes from the UK Standardisation of Breast Radiotherapy (START) trials, results of which were recently published in The Lancet Oncology... Read More
Volasertib* receives FDA Breakthrough Therapy Designation for treatment of patients with acute myeloid leukaemia
Sep 19, 2013
Boehringer Ingelheim Pharmaceuticals, Inc. have announced the FDA has granted Breakthrough Therapy designation to volasertib*, an investigational inhibitor of polo-like kinase (Plk), being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia (AML), ineligible for intensive remission induction therapy... Read More
Discovery of potent tumor-suppressor in lung cancer
Sep 19, 2013
New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells. The preclinical study was led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G... Read More
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