Industry News
Did a risk of skin cancer drive the evolution of black skin in humans?
Feb 26, 2014
A new analysis suggests that black skin may have evolved in humans as a protective measure against skin cancer.Previously, skin cancer has been disregarded as an influence in the evolution of black skin in humans. This is based on the belief that skin cancer only rarely causes death at ages young enough to affect reproduction. Read More
New molecular mechanism pinpointed in autophagy spurs melanoma clinical trial
Feb 26, 2014
Half of melanoma patients with the BRAF mutation have a positive response to treatment with BRAF inhibitors, but nearly all of those patients develop resistance to the drugs and experience disease progression. Read More
Dual targeting approach successfully targets DNA synthesis in leukemic cells
Feb 26, 2014
A novel two-pronged strategy targeting DNA synthesis can treat leukemia in mice, according to a study in The Journal of Experimental Medicine.Current treatments for acute lymphoblastic leukemia (ALL), an aggressive form of blood cancer, include conventional chemotherapy drugs that inhibit DNA synthesis. These drugs are effective but have serious side effects on normal dividing tissues. Read More
ALK-positive non-small cell lung cancer: significant discrepancies between FISH and IHC results for ALK testing
Feb 26, 2014
The findings of a recent study indicate that routine testing with both fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC) may enhance the detection of ALK-positive non-small cell lung cancer (NSCLC). Accurate determination of ALK-positive tumors is necessary to identify patients with advanced NSCLC who are most likely to benefit from targeted therapy with an ALK inhibitor. Read More
Treatment priorities set in new national research effort
Feb 26, 2014
Treatment regimens often evolve without strong scientific evidence of their benefits and drawbacks, particularly in comparison to other drugs or approaches.Now Duke Medicine is participating in a large national initiative aiming to fill in that missing information. Read More
Young women with BRCA1 mutation 'should remove ovaries earlier'
Feb 25, 2014
It is widely known that having a BRCA1 gene mutation increases risk of female breast and ovarian cancers. And now, findings from a large international study suggest that women with these mutations should have preventive surgery to remove the ovaries by the age of 35, rather than waiting until a later age when the risk of ovarian cancer greatly increases. Read More
Young women with BRCA1 mutation 'should remove ovaries earlier'
Feb 25, 2014
It is widely known that having a BRCA1 gene mutation increases risk of female breast and ovarian cancers. And now, findings from a large international study suggest that women with these mutations should have preventive surgery to remove the ovaries by the age of 35, rather than waiting until a later age when the risk of ovarian cancer greatly increases. Read More
Cheap urine test for cancer steps closer
Feb 25, 2014
Non-infectious illnesses like cancer and cardiovascular diseases are rising globally, but they are hard to diagnose because of lack of biomarkers, and in countries with poor infrastructure, expensive diagnosis using mammograms and colonoscopy is not available to many. Read More
Salt imbalance occurs in nearly a third of hospitalised patients
Feb 25, 2014
Simple guidelines for diagnosing and treating a salt imbalance occurring in up to 30% of hospitalised patients are published in the European Journal of Endocrinology. The guidelines recommend that any hospital-based clinician must be able to correctly diagnose, classify and treat hyponatraemia, which is associated with morbidity, mortality and length of hospital stay in a wide range of conditions. Read More
Cheap urine test for cancer steps closer
Feb 25, 2014
Non-infectious illnesses like cancer and cardiovascular diseases are rising globally, but they are hard to diagnose because of lack of biomarkers, and in countries with poor infrastructure, expensive diagnosis using mammograms and colonoscopy is not available to many. Read More
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