Industry News
Epigenetic machinery hijacked by some breast cancer tumors to evade drug therapy
Mar 28, 2014
A breast cancer therapy that blocks estrogen synthesis to activate cancer-killing genes sometimes loses its effectiveness because the cancer takes over epigenetic mechanisms, including permanent DNA modifications in the patient's tumor, once again allowing tumor growth, according to an international team headed by the University of Pittsburgh Cancer Institute (UPCI). Read More
Scientists unravel nerve-cell death in rare children's disease
Mar 28, 2014
A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute (Sanford-Burnham), recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died. Read More
Phase 1 trial finds ceritinib suppresses growth of both crizotinib-resistant and crizotinib-sensitive lung tumors with manageable side effects
Mar 28, 2014
Although the targeted cancer treatment drug crizotinib is very effective in causing rapid regression of a particular form of lung cancer, patients' tumors inevitably become resistant to the drug. Read More
In cancer, resistance and tolerance mechanisms play role as well as infections
Mar 28, 2014
A Stanford University lab whose studies have advanced scientific understanding of resistance and tolerance defense mechanisms to bacterial and viral pathogens has now turned its sights on cancer. Read More
Mood-stabilizing drug may reduce risk of developing head and neck cancer
Mar 28, 2014
A new study indicates that a commonly used mood stabilizing drug may help prevent head and neck cancer. The study is published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Read More
Nanotube coating helps shrink mass spectrometers
Mar 28, 2014
Nanotechnology is advancing tools likened to Star Trek's "tricorder" that perform on-the-spot chemical analysis for a range of applications including medical testing, explosives detection and food safety. Read More
In mouse model of breast cancer peaches inhibit metastasis
Mar 28, 2014
Lab tests at Texas A&M AgriLife Research have shown that treatments with peach extract inhibit breast cancer metastasis in mice.AgriLife Research scientists say that the mixture of phenolic compounds present in the peach extract are responsible for the inhibition of metastasis, according to the study, which was this month published in the Journal of Nutritional Biochemistry. Read More
MRI helps diagnose prostate cancer more accurately
Mar 27, 2014
In a world first, an Australian clinical trial has shown that biopsy guided by MRI can significantly improve the diagnosis of life-threatening prostate cancer and reduce the over-diagnosis of non-life-threatening cases, thus avoiding the side effects of unnecessary treatment. Read More
NICE rejects life-extending bowel cancer drug two weeks after Scottish approval
Mar 27, 2014
NICE announced on 25 March 2014 that it is not recommending ZALTRAP® (aflibercept) to the NHS in England and Wales for the treatment of advanced, metastatic colorectal cancer (mCRC).1 Based on the same basic evidence, aflibercept was approved for use in Scotland on 10 March. Read More
Researchers say gold-based drug shows promise for fighting bone cancer in people and pets
Mar 27, 2014
A gold-based drug currently used in human and veterinary medicine to manage certain immune diseases may prove useful in combating osteosarcoma, a devastating bone cancer that affects both dogs and people, University of Florida veterinary researchers report. Read More
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