Industry News
Testing Combo Therapies To Overcome Drug Resistance In Melanoma Patients
Aug 03, 2011
About 50 to 60 percent of patients with melanoma have a mutation in the BRAF gene that drives the growth of their cancer. Most of these patients respond well to two novel agents being studied in clinical trials that inhibit the gene, with remarkable responses that are, unfortunately, almost always limited in duration... Read More
Late-Stage Ovarian Cancer Therapy Shows Promise In Phase II Trial
Aug 03, 2011
An experimental two-drug combination for treating late-stage ovarian cancer continues to produce strong results, leading its Indiana University researchers to actively pursue the next step, conducting a larger clinical trial to test the therapy and to see how it compares with existing treatments for ovarian cancer... Read More
Two-Drug Combination Produced Strong Results In Late Stage Ovarian Cancer Phase II Trial
Aug 02, 2011
Researchers were surprised that late stage ovarian cancer patients responded well to an experimental carboplatin-decitabine combination therapy, given that they had become resistant to carboplatin. Indiana University researchers are eager to conduct a larger human study to test the two-drug combination with existing treatment for ovarian cancer... Read More
Potential For Improved Cancer Screening With New High-Speed 3-D Imaging System
Aug 02, 2011
Researchers at the Massachusetts Institute of Technology (MIT) have developed a new imaging system that enables high-speed, three-dimensional (3-D) imaging of microscopic pre-cancerous changes in the esophagus or colon... Read More
The Mechanism That Determines Cell Position In The Intestinal Epithelium Discovered By Researchers
Aug 02, 2011
How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers with the Colorectal Cancer Lab at IRB Barcelona have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories... Read More
New Disposable Credit Card-Sized Device Diagnoses Infectious Diseases At Patients' Bedsides, Could Streamline Blood Testing
Aug 02, 2011
Samuel K. Sia, assistant professor of biomedical engineering at Columbia Engineering, has developed an innovative strategy for an integrated microfluidic-based diagnostic device - in effect, a lab-on-a-chip - that can perform complex laboratory assays, and do so with such simplicity that these tests can be carried out in the most remote regions of the world... Read More
Federal Appeals Court Partially Reverses Lower Court's Ruling On Case That Challenges Patents On Two Human Genes
Aug 02, 2011
In a 2-1 decision, a federal appeals court has partially reversed a lower court's ruling in a case challenging patents on two human genes, BRCA1 and BRCA2, associated with hereditary breast and ovarian cancer. The court ruled that companies can obtain patents on the genes but cannot patent methods to compare those gene sequences. The lawsuit, Association for Molecular Pathology, et al. v... Read More
Mechanism Behind 'Oncogene Addiction' In Acute Leukemia Revealed By Scientists
Aug 02, 2011
A team of scientists at Cold Spring Harbor Laboratory (CSHL) has laid bare the mechanism behind a phenomenon called oncogene addiction in mice suffering from a form of leukemia that mimics acute myelogenous leukemia (AML) in humans... Read More
Key Growth Factor Identified In T Cell Leukemia
Aug 02, 2011
Blocking a growth factor receptor cripples cancer growth in a form of T cell leukemia, according to a study published online on August 1 in the Journal of Experimental Medicine. Approximately half of the cases of T cell acute lymphoblastic leukemia (T-ALL) carry genetic mutations in a cellular signaling pathway called Notch, which result in aberrant activation of the cell... Read More
First Molecular Binding Measurement Of Radon
Aug 02, 2011
Even in trace quantities, the radioactive gas radon is very dangerous; it is second only to cigarette smoking as a cause of lung cancer deaths in the United States. The expense and precautions necessary to study it safely have limited research into its properties... Read More
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