Industry News
Resistance To Common Breast Cancer Drug May Be Overcome By Histone Deacetylase Inhibitor
Nov 15, 2011
Researchers have shown how estrogen receptor-positive breast cancer tumors become resistant to tamoxifen, the only approved hormonal therapy for premenopausal patients with this type of breast cancer. They also found that introducing a novel histone deacetylase inhibitor in hormone therapy treatment can overcome resistance to hormonal therapy... Read More
In Mouse Model, Combination Therapy Shows Potent Tumor Growth Inhibition
Nov 15, 2011
Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, being held Nov. 12-16, 2011... Read More
Mammograms: How Often Should Women Have Them?
Nov 15, 2011
While most women already undergo mammograms to check for breast cancer, there has been considerable debate about how frequently women need to be screened. To help answer that question, researchers at the University of Virginia Health System are developing a personalized risk model to recommend how often a woman should have a mammogram based on her unique risk factors... Read More
Newly Identified Gene Mutation Adds To Melanoma Risk
Nov 15, 2011
A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer. The identified mutation occurs in the gene encoding MITF, a transcription factor that induces the production of several important proteins in melanocytes, the cells in which melanoma originates... Read More
Neurological Impairment Associated With Chemotherapy
Nov 14, 2011
A report in the November issue of the Archives of Neurology, one of the JAMA/Archives journals outlines cases of women who survived breast cancer and showed neurological impairment. The problem seems to be markedly worse in those who received chemotherapy compared with those that did not... Read More
Advanced Breast Cancer - First Worldwide Guidelines
Nov 14, 2011
Recently (3-5 November) at a conference in Lisbon, Portugal, experts from around the world agreed on the world's first consensus how to treat and help individuals suffering with advanced breast cancer... Read More
Blood Test Within Weeks Of Treatment Shows Benefit Of Novel Drug In Breast Cancer
Nov 14, 2011
Clinical benefit from use of a novel histone deacetylase inhibitor drug may be determined by examining blood cells days after a patient receives treatment... Read More
Signaling Pathway Linked To Inflammatory Breast Cancer May Drive Disease Metastasis
Nov 14, 2011
Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with inflammatory breast cancer experience. If validated, the use of anaplastic lymphoma kinase (ALK) inhibitors may be a new treatment approach for patients with this lethal form of breast cancer... Read More
Evelyn H. Lauder Dies Of Non-Genetic Ovarian Cancer
Nov 13, 2011
Evelyn Lauder, 75, founder of pink ribbon for cancer awareness, died today from complications of non-genetic ovarian cancer, which had been diagnosed in 2007, at her home in New York City, the Estée Lauder Companies Inc. (ELC) announced today. Her family is said to have been at her bedside as she passed away... Read More
Anti-Cancer Gene Acitivity In Late-Stage Lung Cancer Patients May Be Restored By Combination Epigenetic Therapy
Nov 13, 2011
A new type of therapy aimed at reversing the gene-silencing that promotes cancer-cell growth has shown promising results in a small clinical trial conducted by researchers at the Johns Hopkins Kimmel Cancer Center... Read More
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