Industry News
New Drug Treatment Extends Life In Advanced Prostate Cancer That Has Spread To Bone
Jun 12, 2012
Prostate cancer patients with advanced tumors that have spread to bone have a poor chance of surviving. Patients with the disease may now live longer with a new line of radioisotope therapy, said researchers at the Society of Nuclear Medicine's 2012 Annual Meeting. The skeletal systemis the number one metastatic site in patients with prostate cancer... Read More
News From The Journal Of Clinical Investigation: June 11, 2012
Jun 12, 2012
ALLERGY AND ASTHMA Evidence for a new therapeutic target for inflammatory skin diseases Many chronic inflammatory diseases, including atopic dermatitis and asthma, are initially triggered by an allergic reaction. However, the mechanism through which an allergic reaction becomes a chronic condition remains poorly understood... Read More
Using The Immune System To Fight Cancer
Jun 12, 2012
The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic enzymes. However, mutations have allowed many types of tumors to develop a resistance to NK-mediated killing through ill-defined mechanisms. Dr... Read More
Unusual 'Altruistic' Stem Cell Behavior Identified With Possible Link To Cancer
Jun 12, 2012
When most groups of mammalian cells are faced with a shortage of nutrients or oxygen, the phrase "every man for himself" is more apt than "all for one, one for all." Unlike colonies of bacteria, which often cooperate to thrive as a group, mammalian cells have never been observed to help one another out... Read More
Cells Identified That Are Targeted By HPV, The Origins Of Cervical Cancer
Jun 12, 2012
Virtually all cervical cancers are caused by HPV infections, with just two HPV types, 16 and 18, responsible for about 70 percent of all cases, according to the National Cancer Institute. Scientists have presumed for decades that the cervical cancers that develop from HPV infection arise in a specific location in the cervix... Read More
How Cells' Common Sugar Molecules Influence Inflammation, Cancer Metastasis, And Related Conditions
Jun 12, 2012
Scientists at The Scripps Research Institute have developed chemical compounds that can make key modifications to common sugar molecules ("glycans"), which are found on the surface of all cells in our body... Read More
Breast Tumor Signatures Found That Predict Treatment Response
Jun 12, 2012
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment. Researchers at Washington University School of Medicine in St... Read More
Breast Tumor Signatures Found That Predict Treatment Response
Jun 12, 2012
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment. Researchers at Washington University School of Medicine in St... Read More
ADAM28-Mediated Cancer Metastasis
Jun 12, 2012
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute... Read More
ADAM28-Mediated Cancer Metastasis
Jun 12, 2012
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute... Read More
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